منابع مشابه
Suprachiasmatic nucleus
So what’s the fuss? In mammals, it is the site of an endogenous pacemaker that regulates 24 hour, circadian rhythmicity, synchronizing the phases and periods of a host of behavioral, physiological, and hormonal rhythms to the environmental light–dark cycle. The SCN also appears to function as a seasonal clock underlying the measurement of daylength. The SCN was first implicated as a master cloc...
متن کاملResetting the suprachiasmatic nucleus clock.
Recent research on the cellular basis of circadian rhythmicity has stressed the importance of clock genes for the maintenance of normal rhythmicity. There have been tremendous advances in our understanding of the inter-relationships of the various genes known to generate the rhythms. We know relatively little, however, about the way animals maintain their rhythmicity under normal seasonally cha...
متن کاملCircadian Gene Expression in the Suprachiasmatic Nucleus 901 Circadian Gene Expression in the Suprachiasmatic Nucleus
Regulated expression of a core set of clock genes is the basis of circadian timekeeping in vertebrates, as in other organisms. Clock genes are defined as being necessary to generate normal circadian rhythms, near 24 h oscillations in biological processes. With the enlargement of the brain in vertebrates, control of circadian rhythms became centralized. In lower vertebrates, such as fishes, liza...
متن کاملVasopressin-deficient suprachiasmatic nucleus grafts re-instate circadian rhythmicity in suprachiasmatic nucleus-lesioned arrhythmic rats.
It was investigated whether grafts of the suprachiasmatic nucleus could re-instate circadian rhythmicity in the absence of its endogenous vasopressin production and whether the restored rhythm would have the long period length of the donor. Grafts of 17-days-old vasopressin-deficient homozygous Brattleboro rat fetuses, homotopically placed in arrhythmic suprachiasmatic nucleus-lesioned Wistar r...
متن کاملTransplanted suprachiasmatic nucleus determines circadian period.
The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was tested by neural transplantation by using a mutant strain of hamster that shows a short circadian period. Small neural grafts from the suprachiasmatic region restored circadian rhythms to arrhythmic animals whose own nucleus had been ablated. The restored rhythms always exhibited the period of the donor genoty...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2002
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)01155-7